Motif ID: NFY{A,B,C}.p2

Z-value: 3.886


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma



Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_19035792 7.398 NM_178526
SLC25A42
solute carrier family 25, member 42
chr1_+_144149794 6.654 NM_006472
TXNIP
thioredoxin interacting protein
chr17_+_54587641 6.486 NM_018304
PRR11
proline rich 11
chr7_+_99974781 6.323 AGFG2
ArfGAP with FG repeats 2
chr7_+_99974720 6.095 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr17_-_54587581 5.904 NM_001100595
NM_182620
SKA2

spindle and kinetochore associated complex subunit 2

chr17_+_54587882 5.445 PRR11
proline rich 11
chr17_-_77573974 5.196 NM_144998
STRA13
stimulated by retinoic acid 13 homolog (mouse)
chr17_+_43374021 5.160 PNPO
pyridoxamine 5'-phosphate oxidase
chr17_+_43373887 5.042 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr22_+_36384647 4.991 NM_020315
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr16_-_2204776 4.985 NM_001042371
PGP
phosphoglycolate phosphatase
chr12_-_120725210 4.502 LOC338799
hypothetical LOC338799
chr17_-_54587306 4.445 SKA2
spindle and kinetochore associated complex subunit 2
chr19_+_54160369 4.292 NM_000146
FTL
ferritin, light polypeptide
chr9_-_139084833 4.239 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr14_-_22825148 4.127 NM_020834
HOMEZ
homeobox and leucine zipper encoding
chr17_-_53950191 4.061 NM_004687
MTMR4
myotubularin related protein 4
chr14_-_22825072 4.053 HOMEZ
homeobox and leucine zipper encoding
chr17_+_23670247 4.022 NM_014573
TMEM97
transmembrane protein 97
chr19_+_54160399 3.858 FTL
ferritin, light polypeptide
chr17_-_35827568 3.845 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr6_+_160103500 3.839 ACAT2
acetyl-CoA acetyltransferase 2
chr9_+_130883199 3.778 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr7_+_129497572 3.763 NM_014997
KLHDC10
kelch domain containing 10
chr2_-_96238296 3.745 NM_020151
STARD7
StAR-related lipid transfer (START) domain containing 7
chr1_-_195382189 3.741 NM_018136
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr7_+_129497637 3.703 KLHDC10
kelch domain containing 10
chrX_-_48844929 3.699 NM_007075
WDR45
WD repeat domain 45
chr17_+_34162525 3.687 NM_002795
PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
chr19_+_1442000 3.677 NM_138393
REEP6
receptor accessory protein 6
chr20_-_45418818 3.583 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr11_-_73371945 3.557 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr19_+_54961880 3.538 NM_014203
NM_130787
AP2A1

adaptor-related protein complex 2, alpha 1 subunit

chr7_+_129497808 3.394 KLHDC10
kelch domain containing 10
chr19_+_54962075 3.382 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr20_+_47096280 3.332 CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr6_-_30792830 3.295 MDC1
mediator of DNA-damage checkpoint 1
chr19_-_56561444 3.269 NM_001985
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr12_+_52960745 3.214 NM_002136
NM_031157
HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

chr6_+_43005126 3.212 CNPY3
canopy 3 homolog (zebrafish)
chr11_+_61473931 3.210 NM_001139443
NM_004183
BEST1

bestrophin 1

chr6_+_43005214 3.185 CNPY3
canopy 3 homolog (zebrafish)
chr17_+_44325127 3.168 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr14_+_23175383 3.161 NM_005794
NM_182908
DHRS2

dehydrogenase/reductase (SDR family) member 2

chr15_+_74416156 3.160 NM_145805
ISL2
ISL LIM homeobox 2
chr2_-_96238234 3.159 STARD7
StAR-related lipid transfer (START) domain containing 7
chr1_+_110683586 3.148 RBM15
RNA binding motif protein 15
chr1_+_42920729 3.124 YBX1
Y box binding protein 1
chr17_-_71747867 3.117 NM_052916
RNF157
ring finger protein 157
chr1_+_42920755 3.108 YBX1
Y box binding protein 1
chr20_-_60415729 3.089 NM_031215
CABLES2
Cdk5 and Abl enzyme substrate 2
chrX_+_47999740 3.042 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr15_+_74416129 3.038 ISL2
ISL LIM homeobox 2
chr12_+_52960798 3.028 HNRNPA1L2
HNRNPA1
HNRNPA1P10
heterogeneous nuclear ribonucleoprotein A1-like 2
heterogeneous nuclear ribonucleoprotein A1
heterogeneous nuclear ribonucleoprotein A1 pseudogene 10
chr1_+_110683580 2.991 RBM15
RNA binding motif protein 15
chr16_-_57221235 2.965 CNOT1
CCR4-NOT transcription complex, subunit 1
chr5_+_130534555 2.951 LYRM7
Lyrm7 homolog (mouse)
chr1_+_42920718 2.941 YBX1
Y box binding protein 1
chr20_+_47096189 2.909 NM_001316
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr12_+_56374004 2.867 NM_001017956
NM_001017957
NM_001017958
NM_006812
OS9



osteosarcoma amplified 9, endoplasmic reticulum lectin



chr19_-_10352212 2.862 NM_003331
TYK2
tyrosine kinase 2
chr5_+_130534534 2.838 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr19_+_54160468 2.810 FTL
ferritin, light polypeptide
chr19_-_10352172 2.803 TYK2
tyrosine kinase 2
chr16_-_57221240 2.745 NM_016284
NM_206999
CNOT1

CCR4-NOT transcription complex, subunit 1

chr16_-_57221228 2.742 CNOT1
CCR4-NOT transcription complex, subunit 1
chr1_+_51968046 2.729 NM_148904
NM_148905
NM_148907
OSBPL9


oxysterol binding protein-like 9


chr16_+_10387412 2.717 ATF7IP2
activating transcription factor 7 interacting protein 2
chr1_-_148868671 2.707 ENSA
endosulfine alpha
chr12_+_48003237 2.695 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chrX_-_132947290 2.678 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chr12_+_122283796 2.675 NM_152269
NM_001194995
C12orf65

chromosome 12 open reading frame 65

chr19_+_55398680 2.635 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr7_+_149707338 2.629 NM_173680
ZNF775
zinc finger protein 775
chr5_+_70918856 2.628 NM_022132
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr19_+_54962083 2.608 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr1_+_26433200 2.588 NM_022778
CCDC21
coiled-coil domain containing 21
chr15_+_38520594 2.587 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr5_+_70918888 2.574 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr1_+_42920692 2.570 YBX1
Y box binding protein 1
chr19_-_53832381 2.568 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr12_-_52960206 2.567 CBX5
chromobox homolog 5
chr11_-_19219000 2.547 NM_024680
E2F8
E2F transcription factor 8
chr1_+_42920685 2.543 YBX1
Y box binding protein 1
chr6_-_136613097 2.506 NM_001099286
NM_138419
FAM54A

family with sequence similarity 54, member A

chr17_+_43082273 2.505 NM_002265
KPNB1
karyopherin (importin) beta 1
chr2_+_27128024 2.468 AGBL5
ATP/GTP binding protein-like 5
chr19_-_50912429 2.458


chr6_+_24883133 2.456 NM_015895
GMNN
geminin, DNA replication inhibitor
chrX_-_132947141 2.450 GPC3
glypican 3
chr12_-_108495663 2.446 NM_052845
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type
chr6_-_32253819 2.445 NM_032741
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr17_+_43082302 2.420 KPNB1
karyopherin (importin) beta 1
chr11_-_550706 2.405 NM_173573
C11orf35
chromosome 11 open reading frame 35
chr5_+_70918893 2.396 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr14_+_28305922 2.393 NM_005249
FOXG1
forkhead box G1
chr12_-_55013987 2.391 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr1_+_51968096 2.383 OSBPL9
oxysterol binding protein-like 9
chr20_-_31737731 2.362 E2F1
E2F transcription factor 1
chr9_-_94095734 2.356 IARS
isoleucyl-tRNA synthetase
chr15_+_73278285 2.355 C15orf39
chromosome 15 open reading frame 39
chr1_-_109742020 2.351 NM_002959
SORT1
sortilin 1
chr1_+_51968191 2.340 OSBPL9
oxysterol binding protein-like 9
chr1_+_42920683 2.328 YBX1
Y box binding protein 1
chr1_+_42920774 2.327 YBX1
Y box binding protein 1
chr13_+_48916420 2.325 NM_031915
SETDB2
SET domain, bifurcated 2
chr11_+_550868 2.322 NM_001143993
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr1_+_110683467 2.317 NM_022768
RBM15
RNA binding motif protein 15
chr6_+_31903374 2.299 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr6_+_160103052 2.294 ACAT2
acetyl-CoA acetyltransferase 2
chr1_-_52117021 2.293 NM_001101662
NM_002525
NRD1

nardilysin (N-arginine dibasic convertase)

chr3_-_187771025 2.287 NM_001134415
TBCCD1
TBCC domain containing 1
chr12_+_108495882 2.281 NM_000431
NM_001114185
MVK

mevalonate kinase

chr14_+_38714111 2.277 NM_002687
PNN
pinin, desmosome associated protein
chr1_-_149586298 2.269 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr19_-_4293718 2.268 STAP2
signal transducing adaptor family member 2
chr1_-_52116965 2.264 NRD1
nardilysin (N-arginine dibasic convertase)
chr1_-_151910041 2.263 ILF2
interleukin enhancer binding factor 2, 45kDa
chr17_+_77574476 2.259 NM_144999
LRRC45
leucine rich repeat containing 45
chr2_-_3360467 2.245 NM_003310
TSSC1
tumor suppressing subtransferable candidate 1
chr7_-_156495985 2.229 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chr6_-_31938530 2.228 NEU1
sialidase 1 (lysosomal sialidase)
chr5_+_44844724 2.222 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr14_-_20807346 2.221 NM_001077442
NM_001077443
NM_004500
NM_031314
HNRNPC



heterogeneous nuclear ribonucleoprotein C (C1/C2)



chr15_+_87919744 2.218 NM_152259
C15orf42
chromosome 15 open reading frame 42
chr6_-_33393696 2.213 NM_001145338
ZBTB22
zinc finger and BTB domain containing 22
chr1_-_148868713 2.212 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr5_+_70918935 2.210 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr19_-_12858956 2.206 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr19_+_16083706 2.200 RAB8A
RAB8A, member RAS oncogene family
chr2_+_26862416 2.191 CENPA
centromere protein A
chr5_+_68498704 2.186 CCNB1
cyclin B1
chr1_-_151910080 2.181 ILF2
interleukin enhancer binding factor 2, 45kDa
chr1_-_28113540 2.181 RPA2
replication protein A2, 32kDa
chr20_-_54400628 2.173 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr6_+_31815703 2.171 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6ORF26
MSH5



MSH5-C6orf26 read-through transcript
mutS homolog 5 (E. coli)



chr5_-_150118274 2.170 NM_001135644
DCTN4
dynactin 4 (p62)
chr1_-_148868178 2.166 NM_207045
NM_207046
NM_207047
ENSA


endosulfine alpha


chr1_-_159257486 2.159 F11R
F11 receptor
chr1_-_148868535 2.150 ENSA
endosulfine alpha
chr14_+_23654161 2.136 DCAF11
DDB1 and CUL4 associated factor 11
chr1_-_52116598 2.134 NRD1
nardilysin (N-arginine dibasic convertase)
chr17_-_45196516 2.125 NM_030802
FAM117A
family with sequence similarity 117, member A
chr4_-_174492029 2.116 NM_001130688
NM_002129
HMGB2

high-mobility group box 2

chr1_-_52116994 2.114 NRD1
nardilysin (N-arginine dibasic convertase)
chr1_-_151910057 2.114 ILF2
interleukin enhancer binding factor 2, 45kDa
chr3_+_187771139 2.100 NM_016306
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr12_-_120715937 2.092 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr5_+_68498741 2.084 CCNB1
cyclin B1
chr6_+_160102978 2.080 NM_005891
ACAT2
acetyl-CoA acetyltransferase 2
chr16_-_10943716 2.070 NM_014015
DEXI
Dexi homolog (mouse)
chr13_+_48916526 2.068 SETDB2
SET domain, bifurcated 2
chr17_-_45196465 2.065 FAM117A
family with sequence similarity 117, member A
chr14_-_23653965 2.053 NRL
neural retina leucine zipper
chr7_-_150305933 2.053 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr5_+_145563324 2.051 NM_018989
RBM27
RNA binding motif protein 27
chr19_-_17377383 2.050 NM_004335
BST2
bone marrow stromal cell antigen 2
chr4_-_2233504 2.048 NM_006454
MXD4
MAX dimerization protein 4
chr1_-_151910052 2.046 ILF2
interleukin enhancer binding factor 2, 45kDa
chr5_+_145563305 2.037 RBM27
RNA binding motif protein 27
chr20_+_54400812 2.033 NM_001033521
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr16_-_10943656 2.019 DEXI
Dexi homolog (mouse)
chr14_-_22549168 2.015 NM_001130706
NM_001130708
NM_021944
C14orf93


chromosome 14 open reading frame 93


chr7_+_156496360 2.013 LOC645249
hypothetical LOC645249
chr4_+_166468266 2.000 NM_001017369
NM_006745
SC4MOL

sterol-C4-methyl oxidase-like

chr5_+_68549317 1.994 NM_033281
MRPS36
mitochondrial ribosomal protein S36
chr12_-_55013713 1.990 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr22_+_38770610 1.987 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr8_-_145713959 1.963 NM_004260
RECQL4
RecQ protein-like 4
chr1_+_153545301 1.953 NM_001135821
FDPS
farnesyl diphosphate synthase
chr11_-_2677799 1.952 KCNQ1OT1
KCNQ1 overlapping transcript 1 (non-protein coding)
chr16_-_10943803 1.947 DEXI
Dexi homolog (mouse)
chr12_+_108495999 1.942 MVK
mevalonate kinase
chr1_+_153545351 1.935 FDPS
farnesyl diphosphate synthase
chr8_+_11697588 1.929 NM_004462
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr6_-_31938572 1.928 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr22_-_37481925 1.922 SUN2
Sad1 and UNC84 domain containing 2
chr22_-_37481857 1.918 NM_015374
SUN2
Sad1 and UNC84 domain containing 2
chr1_-_52116894 1.918 NRD1
nardilysin (N-arginine dibasic convertase)
chr1_-_148868664 1.917 ENSA
endosulfine alpha
chr14_-_54438913 1.916 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr16_-_88410523 1.910 NM_000135
NM_001018112
FANCA

Fanconi anemia, complementation group A

chr1_-_47552238 1.909 NM_001048166
NM_003035
STIL

SCL/TAL1 interrupting locus

chr2_+_27127994 1.902 NM_001035507
NM_021831
AGBL5

ATP/GTP binding protein-like 5

chr19_+_45794895 1.901 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr1_-_157313179 1.900 NM_004833
AIM2
absent in melanoma 2
chr8_+_126079900 1.893 NM_003129
SQLE
squalene epoxidase
chr1_-_148868644 1.888 ENSA
endosulfine alpha
chr1_-_209915443 1.885 NM_002497
NEK2
NIMA (never in mitosis gene a)-related kinase 2
chr5_-_137695337 1.883 NM_001790
NM_022809
CDC25C

cell division cycle 25 homolog C (S. pombe)

chr20_-_31737815 1.883 NM_005225
E2F1
E2F transcription factor 1
chr22_+_22703107 1.881 NM_001144931
LOC391322
D-dopachrome tautomerase-like
chr1_+_42920889 1.880 YBX1
Y box binding protein 1
chr3_-_49117169 1.877 NM_005051
QARS
glutaminyl-tRNA synthetase
chr19_-_45948211 1.876 C19orf54
chromosome 19 open reading frame 54
chr3_+_187771192 1.858 DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr9_-_126945536 1.857 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr20_+_54400979 1.853 NM_001324
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr12_-_122283598 1.853 MPHOSPH9
M-phase phosphoprotein 9

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.12 2.76e-22 GO:0007049 cell cycle
2.49 4.33e-22 GO:0051276 chromosome organization
2.48 3.10e-20 GO:0000278 mitotic cell cycle
2.34 3.10e-20 GO:0022403 cell cycle phase
4.69 3.38e-19 GO:0065004 protein-DNA complex assembly
4.31 3.95e-19 GO:0006323 DNA packaging
2.18 5.05e-19 GO:0022402 cell cycle process
4.53 9.12e-19 GO:0071824 protein-DNA complex subunit organization
4.10 3.08e-18 GO:0006333 chromatin assembly or disassembly
1.77 3.90e-18 GO:0006996 organelle organization
4.85 7.61e-18 GO:0006334 nucleosome assembly
3.90 1.04e-17 GO:0071103 DNA conformation change
4.71 1.35e-17 GO:0031497 chromatin assembly
2.98 1.88e-17 GO:0000087 M phase of mitotic cell cycle
4.58 2.23e-17 GO:0034728 nucleosome organization
2.58 1.11e-16 GO:0000279 M phase
2.46 1.45e-15 GO:0006325 chromatin organization
2.88 2.44e-15 GO:0000280 nuclear division
2.88 2.44e-15 GO:0007067 mitosis
2.79 1.97e-14 GO:0048285 organelle fission
1.27 3.44e-13 GO:0044237 cellular metabolic process
2.57 4.18e-13 GO:0051301 cell division
2.58 5.13e-13 GO:0010564 regulation of cell cycle process
1.34 8.46e-13 GO:0044260 cellular macromolecule metabolic process
2.95 1.18e-11 GO:0000075 cell cycle checkpoint
2.89 2.14e-11 GO:0071156 regulation of cell cycle arrest
2.07 2.28e-11 GO:0051726 regulation of cell cycle
1.51 2.79e-11 GO:0090304 nucleic acid metabolic process
1.43 4.62e-10 GO:0071842 cellular component organization at cellular level
1.23 2.27e-09 GO:0044238 primary metabolic process
3.57 3.84e-09 GO:0007059 chromosome segregation
1.37 4.75e-09 GO:0034641 cellular nitrogen compound metabolic process
1.40 5.44e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.20 7.39e-09 GO:0008152 metabolic process
1.40 1.00e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.87 1.02e-08 GO:0000236 mitotic prometaphase
1.35 1.23e-08 GO:0006807 nitrogen compound metabolic process
1.41 1.63e-08 GO:0009058 biosynthetic process
2.33 5.78e-08 GO:0051325 interphase
2.21 6.69e-08 GO:0034622 cellular macromolecular complex assembly
2.34 7.27e-08 GO:0051329 interphase of mitotic cell cycle
1.33 1.23e-07 GO:0016043 cellular component organization
1.40 1.58e-07 GO:0044249 cellular biosynthetic process
1.11 2.04e-07 GO:0009987 cellular process
1.24 4.57e-07 GO:0043170 macromolecule metabolic process
5.47 5.31e-07 GO:0006695 cholesterol biosynthetic process
1.79 7.51e-07 GO:0065003 macromolecular complex assembly
1.30 1.42e-06 GO:0071840 cellular component organization or biogenesis
1.85 2.09e-06 GO:0006259 DNA metabolic process
4.89 2.12e-06 GO:0016126 sterol biosynthetic process
1.29 2.82e-06 GO:0031323 regulation of cellular metabolic process
1.93 2.92e-06 GO:0034621 cellular macromolecular complex subunit organization
1.29 4.40e-06 GO:0080090 regulation of primary metabolic process
1.46 4.45e-06 GO:0034645 cellular macromolecule biosynthetic process
1.45 7.77e-06 GO:0009059 macromolecule biosynthetic process
1.66 1.21e-05 GO:0043933 macromolecular complex subunit organization
1.25 3.43e-05 GO:0019222 regulation of metabolic process
2.44 5.82e-05 GO:0006260 DNA replication
1.28 6.35e-05 GO:0060255 regulation of macromolecule metabolic process
1.34 7.52e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.98 8.67e-05 GO:0016568 chromatin modification
1.30 1.39e-04 GO:0051171 regulation of nitrogen compound metabolic process
2.13 1.39e-04 GO:0007346 regulation of mitotic cell cycle
1.35 1.55e-04 GO:0006355 regulation of transcription, DNA-dependent
4.01 2.73e-04 GO:0000819 sister chromatid segregation
1.33 2.94e-04 GO:0051252 regulation of RNA metabolic process
1.39 3.45e-04 GO:0016070 RNA metabolic process
1.96 3.73e-04 GO:0006281 DNA repair
1.59 3.98e-04 GO:0033554 cellular response to stress
1.30 4.05e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 6.29e-04 GO:0010556 regulation of macromolecule biosynthetic process
2.53 6.81e-04 GO:0006310 DNA recombination
1.75 7.20e-04 GO:0006974 response to DNA damage stimulus
1.29 1.60e-03 GO:0010468 regulation of gene expression
2.97 1.68e-03 GO:0007088 regulation of mitosis
2.97 1.68e-03 GO:0051783 regulation of nuclear division
1.28 1.68e-03 GO:0009889 regulation of biosynthetic process
1.48 2.01e-03 GO:0022607 cellular component assembly
1.28 2.40e-03 GO:0031326 regulation of cellular biosynthetic process
2.17 2.50e-03 GO:0006457 protein folding
5.90 2.50e-03 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
3.82 3.07e-03 GO:0000070 mitotic sister chromatid segregation
2.57 3.36e-03 GO:0031570 DNA integrity checkpoint
2.38 4.29e-03 GO:0000082 G1/S transition of mitotic cell cycle
1.28 5.36e-03 GO:0044267 cellular protein metabolic process
1.33 5.87e-03 GO:0010467 gene expression
1.62 6.41e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.62 6.86e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42 7.27e-03 GO:0044085 cellular component biogenesis
2.43 8.34e-03 GO:0007093 mitotic cell cycle checkpoint
4.46 1.01e-02 GO:0031576 G2/M transition checkpoint
1.65 1.33e-02 GO:0044265 cellular macromolecule catabolic process
1.53 1.37e-02 GO:0071844 cellular component assembly at cellular level
4.30 1.61e-02 GO:0006271 DNA strand elongation involved in DNA replication
2.21 1.69e-02 GO:0010498 proteasomal protein catabolic process
2.21 1.69e-02 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
5.01 1.80e-02 GO:0008299 isoprenoid biosynthetic process
1.58 2.07e-02 GO:0009057 macromolecule catabolic process
1.45 2.45e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.87 2.62e-02 GO:0006302 double-strand break repair
4.01 3.78e-02 GO:0022616 DNA strand elongation
1.39 4.17e-02 GO:0044248 cellular catabolic process
2.70 4.35e-02 GO:0000216 M/G1 transition of mitotic cell cycle
1.55 4.81e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.39 4.86e-02 GO:0000086 G2/M transition of mitotic cell cycle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.35 9.53e-51 GO:0043227 membrane-bounded organelle
1.35 2.40e-50 GO:0043231 intracellular membrane-bounded organelle
1.31 6.09e-49 GO:0043226 organelle
1.30 2.13e-48 GO:0043229 intracellular organelle
1.24 2.60e-47 GO:0044424 intracellular part
1.23 1.71e-45 GO:0005622 intracellular
1.45 2.09e-34 GO:0005634 nucleus
2.92 6.19e-34 GO:0005694 chromosome
1.42 1.03e-30 GO:0044446 intracellular organelle part
3.01 2.01e-30 GO:0044427 chromosomal part
1.42 4.00e-30 GO:0044422 organelle part
1.66 2.51e-21 GO:0070013 intracellular organelle lumen
1.63 4.51e-20 GO:0043233 organelle lumen
1.62 5.55e-20 GO:0031974 membrane-enclosed lumen
3.31 9.52e-20 GO:0000785 chromatin
1.61 1.26e-17 GO:0044428 nuclear part
1.43 2.42e-16 GO:0032991 macromolecular complex
1.21 4.97e-15 GO:0005737 cytoplasm
1.62 7.43e-15 GO:0031981 nuclear lumen
5.18 6.41e-14 GO:0000786 nucleosome
1.46 1.03e-13 GO:0043228 non-membrane-bounded organelle
1.46 1.03e-13 GO:0043232 intracellular non-membrane-bounded organelle
1.72 1.75e-13 GO:0005654 nucleoplasm
4.14 2.26e-13 GO:0032993 protein-DNA complex
1.26 6.51e-13 GO:0044444 cytoplasmic part
3.15 7.26e-10 GO:0000793 condensed chromosome
2.83 5.56e-09 GO:0044454 nuclear chromosome part
3.02 6.73e-09 GO:0000775 chromosome, centromeric region
1.36 7.66e-09 GO:0043234 protein complex
1.83 1.44e-08 GO:0044429 mitochondrial part
2.58 1.59e-08 GO:0000228 nuclear chromosome
1.54 7.32e-08 GO:0005739 mitochondrion
2.49 2.14e-06 GO:0005819 spindle
1.72 2.19e-06 GO:0015630 microtubule cytoskeleton
3.34 6.56e-06 GO:0000779 condensed chromosome, centromeric region
3.15 7.83e-06 GO:0000776 kinetochore
7.16 2.86e-05 GO:0042613 MHC class II protein complex
1.04 2.95e-05 GO:0044464 cell part
1.04 3.06e-05 GO:0005623 cell
3.30 3.16e-05 GO:0000777 condensed chromosome kinetochore
2.12 3.93e-05 GO:0005759 mitochondrial matrix
1.60 1.70e-04 GO:0031967 organelle envelope
3.46 3.05e-04 GO:0000794 condensed nuclear chromosome
1.57 4.05e-04 GO:0031975 envelope
1.32 4.45e-04 GO:0005829 cytosol
3.14 5.05e-04 GO:0000922 spindle pole
1.56 8.81e-04 GO:0044451 nucleoplasm part
7.02 3.94e-03 GO:0008250 oligosaccharyltransferase complex
1.65 4.23e-03 GO:0005740 mitochondrial envelope
1.60 8.11e-03 GO:0030529 ribonucleoprotein complex
1.91 1.15e-02 GO:0016604 nuclear body
1.86 2.83e-02 GO:0005813 centrosome
1.58 3.63e-02 GO:0031966 mitochondrial membrane
4.30 4.07e-02 GO:0000795 synaptonemal complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.44 1.13e-15 GO:0003676 nucleic acid binding
1.50 1.06e-12 GO:0003677 DNA binding
1.12 4.71e-12 GO:0005488 binding
1.17 2.93e-07 GO:0005515 protein binding
1.53 5.95e-05 GO:0030528 transcription regulator activity
2.20 6.33e-04 GO:0003682 chromatin binding
1.15 4.88e-03 GO:0003824 catalytic activity
1.33 1.02e-02 GO:0005524 ATP binding
1.32 1.19e-02 GO:0030554 adenyl nucleotide binding
1.25 1.42e-02 GO:0000166 nucleotide binding
1.32 1.78e-02 GO:0032559 adenyl ribonucleotide binding
6.68 4.46e-02 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
1.27 4.55e-02 GO:0035639 purine ribonucleoside triphosphate binding